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. 2015 Sep 3;126(25):2704–2712. doi: 10.1182/blood-2015-05-647453

Table 1.

Peripheral blood cell counts

wt RIAM−/− Talin-1−/−
White blood cells, K/µL 6.52 ± 2.43 17.12 ± 7.38* 57.37 ± 31.24*
Neutrophils, K/µL 1.50 ± 0.87 5.63 ± 3.38 47.37 ± 29.44*
Lymphocytes, K/µL 4.50 ± 1.43 9.98 ± 3.64* 6.5 ± 2.98
Monocytes, K/µL 0.40 ± 0.22 0.93 ± 0.49 1.51 ± 0.64*
Eosinophils, K/µL 0.10 ± 0.13 0.44 ± 0.55 1.52 ± 1.59
Basophils, K/µL 0.03 ± 0.04 0.19 ± 0.30 0.31 ± 0.48
Red blood cells, M/µL 9.57 ± 0.92 9.49 ± 0.83 5.28 ± 1.67*
Hemoglobin, g/dL 12.90 ± 1.30 13.09 ± 1.61 6.47 ± 3.12*
Hematocrit, % 45.16 ± 4.20 44.12 ± 7.73 24.11 ± 9.03*
Platelets, K/µL 609 ± 115 560 ± 96 927 ± 405

Peripheral blood cell counts of wt (n = 12), RIAM−/− (n = 18), and talin-1fl/fl/Mx1-Cre (Talin-1−/−) mice (n = 9). Talin-1 deletion was induced with poly-IC and blood counts were measured 10 days later. Values are given as mean ± SD.

*

P < .001.

P < .01.