Table 1.
Peripheral blood cell counts
wt | RIAM−/− | Talin-1−/− | |
---|---|---|---|
White blood cells, K/µL | 6.52 ± 2.43 | 17.12 ± 7.38* | 57.37 ± 31.24* |
Neutrophils, K/µL | 1.50 ± 0.87 | 5.63 ± 3.38† | 47.37 ± 29.44* |
Lymphocytes, K/µL | 4.50 ± 1.43 | 9.98 ± 3.64* | 6.5 ± 2.98 |
Monocytes, K/µL | 0.40 ± 0.22 | 0.93 ± 0.49† | 1.51 ± 0.64* |
Eosinophils, K/µL | 0.10 ± 0.13 | 0.44 ± 0.55 | 1.52 ± 1.59† |
Basophils, K/µL | 0.03 ± 0.04 | 0.19 ± 0.30 | 0.31 ± 0.48 |
Red blood cells, M/µL | 9.57 ± 0.92 | 9.49 ± 0.83 | 5.28 ± 1.67* |
Hemoglobin, g/dL | 12.90 ± 1.30 | 13.09 ± 1.61 | 6.47 ± 3.12* |
Hematocrit, % | 45.16 ± 4.20 | 44.12 ± 7.73 | 24.11 ± 9.03* |
Platelets, K/µL | 609 ± 115 | 560 ± 96 | 927 ± 405 |
Peripheral blood cell counts of wt (n = 12), RIAM−/− (n = 18), and talin-1fl/fl/Mx1-Cre (Talin-1−/−) mice (n = 9). Talin-1 deletion was induced with poly-IC and blood counts were measured 10 days later. Values are given as mean ± SD.
P < .001.
P < .01.