Fig. 1.

Effect of 7 days of chronic intermittent hypoxia (CIH) on mean arterial pressure (MAP) and heart rate (HR) during the light phase (left) and the normoxic dark phase (right). All rats were normoxic for 3 days of baseline (c). Data shown for the light phase are mean pressures from 0800 to 1600 during CIH (ih). Following CIH exposure, rats were allowed to recover for 3 days (p). Animals in subsequent experiments were killed on the morning following ih7. CON, control. *P < 0.05 vs. control and CIH; both control and CIH groups n = 6–8 rats. [From Knight et al. (28).]