Table 1.
Characteristics of patients with PAH and healthy controls.
| Variable | PAH patient, n=7 | Control, n=7 | p Value |
|---|---|---|---|
| Age,years | 30.9±7.3 | 30.6±4.2 | 0.930 |
| Gender, M/F | 3/4 | 3/4 | 1.000 |
| FC, II/III | 6/1 | - | - |
| BMI, kg/m2 | 26.3±6.7 | 24.8±3.4 | 0.611 |
| Heart rate, bpm | 84.6±8.6 | 69.3±6.2 | 0.012 |
| Syst. BP, mmHg | 120.8±10.7 | 117.8±7.6 | 0.590 |
| Diast. BP, mmHg | 82.8±11.7 | 79.1±7.4 | 0.530 |
| Hypertension, n (%) | 1 (14.3) | - | - |
| 6-MWT, m | 361.1±69.4 | > 580 male* | - |
| > 500 female* | |||
| NT-proBNP, pg/ml | 3101±1952 | < 85.8 male* | - |
| < 130 female* | |||
| mPAP, mmHg | 58.9±16.3 | 7-19* | - |
| PAWP, mmHg | 9.5±3.1 | 5-13* | |
| PVR, dyn sec m2/cm5 | 1052±494 | 11-99* | - |
| CO, L/min | 3.46 (3.22, 4.16) | 4.4–8.4* | - |
| CI, L/min/m2 | 2.00 (1.88, 2.27) | 2.6–4.2* | - |
| FEV1, % | 79.0±6.5 | - | - |
| VC, % | 76.0±7.5 | - | - |
Data are presented as mean±SD or median (interquartile range).
*
Values were taken from [50]; PAH=pulmonary arterial hypertension; M/F=male/female; FC=functional class; BMI=body mass index; 6MWT=6-min walk test; NT-proBNP=N-terminal pro-brain natriuretic peptide; mPAP=mean pulmonary arterial pressure; PAWP – pulmonary artery wedge pressure; PVR=pulmonary vascular resistance; CO=cardiac output; CI=cardiac index; FEV1 – forced expiratory volume in 1 s; VC- vital capacity.