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. 2015 Dec 18;9:472. doi: 10.3389/fncel.2015.00472

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Copyright © 2015 Perez-Garcia.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Parvalbumin positive interneurons are reduced in the KO mice. (A) Cortical sections immunostained for Parvalbumin (PV) at P21 show a reduction in the number of PV+ interneurons. (B,C) Quantitation analysis at P21 (B) and adult (C). PV+ interneurons in the KO are significantly reduced by 59% at P21 (0.41 ± 0.07, p = 0.0001^∗∗∗, N = 12) and by 46% in the adult (0.54 ± 0.08, p = 0.0001^∗∗∗, N = 6). Scale bar: 100 μm.