Table 3. The association between rs2843710 SNP and severity of EV71 HFMD.
| SNP ID | Genotype | HD | M-EV71 | S-EV71 | M-EV71 Vs HD | S-EV71 Vs HD | S-EV71 Vs M-EV71 | |||
|---|---|---|---|---|---|---|---|---|---|---|
| No (%) | No (%) | No (%) | P Value | OR (95% CI) | P Value | OR (95% CI) | P Value | OR (95% CI) | ||
| rs2843710 | CC | 251 (43.8) | 310 (38.7) | 132 (33.4) | 0.0053 | 1.25(1.07–1.47) | < 0.0001 | 1.52(1.26–1.84) | 0.0289 | 1.21(1.02–1.44) |
| CG | 269 (46.9) | 375 (46.8) | 190 (48.1) | |||||||
| GG | 53 (9.3) | 116 (14.5) | 73 (18.5) | |||||||
Note: Hardy-Weinberg equilibrium P values of rs2843710 were 0.11 in HD, and were 0.88 in M-EV71, and were 0.75 in S-EV71. Abbreviations: HD, healthy donors; M-EV71, mild EV71 HFMD; S-EV71, severe EV71 HFMD; CI, confidence interval; OR, odds ratio.