Table 1. Effects of Harmaline on haematological parameters and the level of ALT, AST in the serum.
Group | WBC | RBC | HGB | PLT | ALT | AST |
---|---|---|---|---|---|---|
(n = 6) | (×109/L) | (×109/L) | (g/L) | (×109/L) | (U/L) | (U/L) |
Control | 9.4 ± 0.1 | 9.0 ± 0.1 | 144.2 ± 8.6 | 964.2 ± 23.4 | 53.2 ± 2.2 | 62.4 ± 2.5 |
Low does | 9.1 ± 0.5 | 9.1 ± 0.2 | 147.5 ± 3.6 | 962.7 ± 11.2 | 52.2 ± 1.8 | 60.9 ± 3.8 |
Median does | 8.8 ± 0.5 | 8.9 ± 0.1 | 142.0 ± 8.2 | 948.3 ± 10.4 | 51.0 ± 1.6 | 59.0 ± 2.6 |
High does | 8.2 ± 0.8* | 8.6 ± 0.4 | 134.0 ± 6.5 | 913.5 ± 26.0 | 68.9 ± 9.5* | 69.7 ± 6.7 |
Note:1 WBC: white blood cells; RBC: red blood cells; HGB: hemoglobulin; PLT: platelet; AST: aspartate aminotransferase; ALT: alanine aminotransferase.
2 The values are expressed as mean ± SD of six mice per group.
3 *Significantly different from the control group.