Skip to main content
. 2015 Dec 1;35(12):969–980. doi: 10.1089/jir.2014.0235

FIG. 6.

FIG. 6.

Protein levels of Bcl-2/Bim in CD4+CD25− T cells after CLP induced sepsis. (A) Using Western blot, Bcl-2 and Bim protein expressions were determined both in vivo and in vitro. (B) Expression of antiapoptotic protein Bcl-2 in CD4+CD25− T cells was significantly decreased after septic challenge (P<0.01), while expression of proapoptotic protein Bim was enhanced (P<0.01). Conversely, Bcl-2 expression was increased and Bim expression was decreased by use of PC61 or anti-TGF-β antibody. Statistical significance: *P<0.01 as CLP group versus sham group; #P<0.01 as PC61 group versus CLP group, or anti-TGF-β antibody group versus anti-TGF-β antibody treatment void group.