Fig. 2.
Sensitization potential after dermal exposure to butter flavorings. Analysis of the sensitization potential of 2,3-hexanedione (A), 3,4-hexanedione (B), 2,3- heptanedione (C), 2,3-pentanedione (D), and diacetyl (E) using the LLNA. 3H-thymidine incorporation into draining lymph node cells of BALB/c mice following exposure to vehicle or concentration of butter flavoring shown above. Bars represent means ± SE of 5 mice per group. Levels of statistical significance are denoted as **(p ≤ 0.01) as compared to acetone vehicle.