Table 2.

MRI image acquisition and processing

MRI Image Type		T1-weighted Hi-Res	DTI	T2-weighted FLAIR	T2-weighted	rs-fMRI
Image Acquisition	Slice Thickness	1 mm	3 mm	3 mm	3 mm	3 mm
	Resolution	256×224 mm	128×128 mm	256×240 mm	256×224 mm	128×128 mm
	Field of View	256×224 mm	256×256 mm	256×212 mm	256×224 mm	256×256 mm(a)
	Repetition Time	2300 ms	5300 ms	9160 ms	3000 ms	2000 ms
	Echo Time	3.43 ms	88 ms	88 ms	11/101 ms	34 ms
	Inversion Time	900 ms	2500 ms	2500 ms	100 ms	n/a
	Flip Angle	9°	90°	150°	150°	90°
	Other	axial plane	axial plane	axial plane	axial plane	axial plane; integrated parallel acquisition technique = 2; gradient-echo-planar imaging sequence
Image Processing (See Supplementary Table 1 for more details on feature acquisition using image processing)		Refer to Wu et al., 2006 for processing pipeline. For more details on the modified version of this pipeline used for this study, see Supplementary Table 2.	FMRIB Software Library (59) was used to preprocess images, acquire Mean Diffusivity (MD) and Fractional Anisotropy (FA) maps, and perform tractography.	Refer to Wu et al., 2006 for the processing pipeline.	Used for rs-fMRI preprocessing.	CONN toolbox (60) was used to preprocess images, extract resting state signals, and performing Fisher transformed correlations between ROIs.

^(a)For the rs-fMRI images, the field of view did not fully cover the cerebellum for most subjects