Table 2. Up-regulated DEGs in cSCNT and fSCNT blastocysts against IVF.
Symbol | refSeq | Chr | cSCNT/IVF | fSCNT/IVF | ||
---|---|---|---|---|---|---|
Fold Change | P-Value | Fold Change | P-Value | |||
CCR7 | NM_001024930 | 19 | 7.47 | 2.5E-02 | 6.92 | 4.0E-02 |
LOC618696 | XR_083836 | 13 | 6.64 | 9.8E-03 | 5.00 | 4.1E-02 |
CADPS | NM_001076020 | 22 | 5.46 | 3.2E-05 | 4.58 | 8.9E-04 |
PTPRD | XM_003586379 | 8 | 5.18 | 3.0E-03 | 5.25 | 3.7E-03 |
ARMCX4 | XM_003588124 | X | 5.09 | 3.3E-04 | 2.97 | 4.3E-02 |
LOC526966 | XM_002700268 | X | 5.03 | 1.9E-02 | 5.98 | 4.9E-03 |
SPECC1 | XM_002695819 | 19 | 5.02 | 1.8E-02 | 5.09 | 1.8E-02 |
LOC100847564 | XR_139737 | X | 4.78 | 4.8E-02 | 5.81 | 2.1E-02 |
SLC38A5 | NM_001015580 | X | 4.78 | 8.8E-03 | 4.38 | 2.1E-02 |
FGF16 | NM_001192777 | X | 4.77 | 5.6E-03 | 2.88 | 4.6E-02 |
LOC100140788 | XR_084090 | 27 | 4.64 | 1.2E-03 | 3.11 | 1.2E-02 |
LOC781710 | XM_002686247 | 3 | 4.56 | 3.4E-04 | 3.56 | 4.3E-03 |
DOK5 | NM_001075939 | 13 | 4.55 | 6.4E-03 | 5.46 | 2.0E-03 |
SOHLH2 | XM_002691802 | 12 | 4.55 | 1.7E-05 | 4.01 | 9.2E-05 |
ULBP3 | NM_001103233 | 17 | 4.29 | 1.7E-02 | 3.91 | 2.4E-02 |
LOC782781 | NM_001168605 | 3 | 4.26 | 3.8E-03 | 3.87 | 7.3E-03 |
NELL2 | NM_001102084 | 5 | 4.25 | 1.6E-02 | 3.59 | 4.0E-02 |
FER1L6 | XM_002692627 | 14 | 4.19 | 1.8E-02 | 5.38 | 2.1E-03 |
ADAMTS4 | NM_181667 | 3 | 3.76 | 2.9E-02 | 4.23 | 2.1E-02 |
PPFIA2 | XM_002687191 | 5 | 3.74 | 1.4E-02 | 3.09 | 2.9E-02 |
LOC787130 | XM_002700111 | X | 3.64 | 8.8E-05 | 3.49 | 2.1E-04 |
NR4A1 | NM_001075911 | 5 | 3.38 | 7.8E-04 | 2.03 | 4.9E-02 |
PAH | NM_001046058 | 5 | 3.31 | 2.4E-02 | 4.05 | 8.1E-03 |
EGR3 | XM_003586409 | 8 | 3.20 | 1.6E-02 | 4.06 | 7.7E-03 |
ISCA2 | NM_001038683 | 10 | 3.11 | 1.7E-02 | 3.49 | 4.2E-03 |
ALDOC | NM_001097984 | 19 | 3.02 | 6.3E-03 | 2.37 | 2.9E-02 |
LOC525414 | XM_003587677 | 23 | 2.99 | 5.8E-03 | 3.26 | 2.7E-03 |
TUBA3E | NM_001038163 | 17 | 2.98 | 3.7E-04 | 3.16 | 2.3E-04 |
SAT1 | NM_001034333 | X | 2.87 | 8.1E-03 | 2.22 | 4.5E-02 |
SYTL2 | NM_001102278 | 29 | 2.87 | 2.2E-02 | 6.02 | 2.3E-07 |
TEK | NM_173964 | 8 | 2.75 | 1.3E-03 | 2.72 | 1.1E-03 |
COL6A2 | NM_001075126 | 1 | 2.70 | 3.8E-02 | 2.79 | 3.4E-02 |
SLC16A6 | NM_001192672 | 19 | 2.68 | 6.6E-06 | 2.41 | 5.2E-05 |
C8H9orf64 | NM_001076978 | 8 | 2.53 | 2.4E-02 | 2.90 | 8.8E-03 |
FBP1 | NM_001034447 | 8 | 2.44 | 3.7E-02 | 2.64 | 3.4E-02 |
LOC100335242 | XM_003585627 | 1 | 2.42 | 4.2E-04 | 1.60 | 1.7E-02 |
SYCP2 | XM_002692264 | 13 | 2.41 | 3.0E-03 | 2.03 | 1.7E-02 |
H1F0 | NM_001076487 | 5 | 2.40 | 2.8E-02 | 2.51 | 2.0E-02 |
HSPA1A | NM_203322 | 23 | 2.40 | 1.3E-03 | 3.29 | 7.4E-05 |
ZNF133 | NM_001110090 | 13 | 2.38 | 2.2E-02 | 2.23 | 2.5E-02 |
IMPDH1 | NM_001077841 | 4 | 2.16 | 9.5E-04 | 1.91 | 4.0E-03 |
HAVCR1 | XM_002683662 | 7 | 2.09 | 1.1E-03 | 1.90 | 3.6E-03 |
AKIP1 | NM_001034203 | 15 | 1.92 | 3.8E-02 | 2.13 | 2.3E-02 |
FHOD3 | NM_001191215 | 24 | 1.92 | 2.2E-02 | 2.14 | 1.4E-02 |
AIFM2 | NM_001040556 | 28 | 1.84 | 1.9E-02 | 1.75 | 3.9E-02 |
TUBB3 | NM_001077127 | 18 | 1.78 | 7.4E-07 | 1.48 | 1.2E-05 |
LOC100848375 | XR_139401 | 11 | 1.78 | 2.2E-03 | 1.74 | 4.3E-03 |
XIST | NR_001464 | X | 1.76 | 8.5E-04 | 2.23 | 4.2E-05 |
ZSWIM6 | XM_002696311 | 20 | 1.74 | 4.3E-05 | 1.26 | 5.4E-03 |
FMNL3 | NM_001191506 | 5 | 1.72 | 2.0E-02 | 1.88 | 1.2E-02 |
CHN1 | NM_001075349 | 2 | 1.72 | 1.6E-02 | 1.96 | 8.9E-03 |
CDH26 | XM_002692262 | 13 | 1.63 | 1.8E-06 | 1.59 | 2.9E-06 |
CDKN2AIP | XM_003587947 | 27 | 1.59 | 4.0E-04 | 1.09 | 1.1E-02 |
HAUS7 | NM_001102277 | X | 1.57 | 3.3E-03 | 1.99 | 5.8E-04 |
DDIT3 | NM_001078163 | 5 | 1.54 | 6.2E-03 | 1.52 | 3.0E-03 |
SERINC5 | XM_002690460 | 10 | 1.45 | 2.2E-02 | 2.23 | 1.8E-03 |
CSTF2 | NM_174685 | X | 1.41 | 3.3E-04 | 1.09 | 2.2E-03 |
JMY | XM_002690458 | 10 | 1.30 | 4.0E-02 | 1.66 | 6.2E-03 |
GBA | NM_001046421 | 3 | 1.23 | 1.7E-04 | 1.32 | 8.4E-05 |
GRIPAP1 | NM_001193106 | X | 1.22 | 2.1E-03 | 1.29 | 3.3E-03 |
ADCY2 | XM_002696432 | 20 | 1.20 | 1.8E-02 | 1.35 | 5.7E-03 |
RBMX2 | NM_001206548 | X | 1.19 | 8.2E-04 | 1.39 | 9.8E-05 |
SLITRK2 | XM_002699621 | X | 1.19 | 2.0E-03 | 1.38 | 1.0E-03 |
CHCHD7 | NM_001130759 | 14 | 1.18 | 8.6E-03 | 1.41 | 4.9E-03 |
PM20D1 | NM_001038100 | 16 | 1.17 | 1.1E-02 | 1.22 | 1.4E-02 |
NDUFB11 | NM_001033620 | X | 1.15 | 2.6E-03 | 1.43 | 9.1E-05 |
CNNM4 | NM_001205896 | 11 | 1.15 | 7.6E-03 | 1.23 | 5.2E-03 |
BCAP31 | NM_001014941 | X | 1.15 | 6.2E-05 | 1.13 | 2.3E-04 |
HECW2 | XM_002685474 | 2 | 1.14 | 1.3E-02 | 1.19 | 8.4E-03 |
ATG3 | NM_001075364 | 1 | 1.14 | 1.9E-02 | 1.22 | 9.5E-03 |
TRAF4 | NM_001101280 | 19 | 1.11 | 1.7E-02 | 1.23 | 8.1E-03 |
PELI2 | XM_002690952 | 10 | 1.11 | 7.4E-03 | 1.61 | 3.7E-04 |
WDR45 | NM_001076151 | X | 1.09 | 2.1E-04 | 1.06 | 2.2E-04 |
COQ10B | NM_001075654 | 2 | 1.07 | 1.8E-02 | 1.39 | 3.8E-03 |
SRGAP2 | NM_001205865 | 16 | 1.05 | 1.7E-02 | 1.30 | 4.9E-03 |
ENPP1 | NM_001206212 | 9 | 1.05 | 2.2E-02 | 1.21 | 4.6E-03 |
SCNM1 | NM_001034254 | 3 | 1.04 | 9.1E-03 | 1.14 | 3.0E-03 |
LOC782021 | XR_084028 | 22 | 1.01 | 3.6E-03 | 1.78 | 5.4E-07 |
DEGs, differentially expressed genes; cSCNT, cumulus cells somatic cell nuclear transfer; fSCNT, adult ear skin fibroblasts somatic cell nuclear transfer; IVF, in vitro fertilization.