Table 3. Differentially expressed genes in different categories important for blastocyst development.
| Category (No. Genes) | cSCNT/IVF | fSCNT/IVF | ||
|---|---|---|---|---|
| cSCNT-Low | cSCNT-High | fSCNT-Low | fSCNT-High | |
| PGs (100) | EPHA4 | DIPH2, DPPA2, TTF1 | FGF13, SALL2, KIT, SALL4, MSH2 | SMAD4 |
| TGs (27) | CCKBR, GCM1, PCAM, PRELID1, ESRRB | − | CCKBR, CDX2 | CSRP2BP |
| DRGs (51) | − | TUBB3 | GATA4, TAB1 | FOXJ3, TUBB3 |
| EMGs (89) | HDAC9, HDAC3, EZH1 | HDAC4, KDM1B, JMJD6, HDAC7, KDM5C, RBBP8 | JMJD5, HDAC9, HDAC3 | KDM6A, TET3, ELP3, SETD1A, PRMT5, PRMT3, KDM5C, KDM3A, EZH2, SETD7, RBBP8 |
P-value < 0.05. cSCNT, cumulus cells somatic cell nuclear transfer; fSCNT, adult ear skin fibroblasts somatic cell nuclear transfer; IVF, in vitro fertilization; PGs, pluripotency-related genes; TGs, genes involved in TE development; DRGs, genes encoding developmental regulators; EMGs, genes encoding epigenetic modifiers.