Table 1. Phenotypes measured in the eight founder strains of the Collaborative Cross.
| Trait | No. Samples | Range of Samples per Founder | Figure | h2 |
|---|---|---|---|---|
| Age | 248 | na | Figure S1 | na |
| Weights | ||||
| Body | 231 | 19−38 | Figure 1A | 0.84 |
| Mean testis | 218 | 20−38 | Figure 1B | 0.71 |
| Mean epididymis + vas deferens | 170 | 12−30 | Figure 1C | 0.70 |
| Seminal vesicles | 217 | 20−38 | Figure 1D | 0.51 |
| Histology | ||||
| Number of tubules | 208 | 17−36 | Figure 3A | 0.50 |
| Mean tubule radius | 208 | 17−36 | Figure 3B | 0.57 |
| Seminiferous epithelium length | 208 | 17−36 | Figure 3C | 0.48 |
| # of tubules with vacuoles | 207 | 16−36 | Figure 4A | 0.35 |
| # of tubules with many vacuoles | 207 | 16−36 | Figure 4B | 0.39 |
| # of tubules with germ cell loss | 141 | 12−26 | Figure S4 | 0.15 |
| # of tubules with abnormal germ cells | 207 | 16−36 | Figure S4 | 0.12 |
| # of tubules with germ cell sloughing | 207 | 16−36 | na | 0.11 |
| Sperm count | ||||
| 106/mouse | 171 | 9−32 | Figure 6A | 0.38 |
| 103/mg testis | 159 | 9−30 | Figure 6B | 0.27 |
| 103/seminiferous epithelium length | 152 | 8−28 | Figure 6C | 0.22 |
| Sperm morphology | ||||
| % normal | 111 | 10−19 | Figure 7A | 0.47 |
| % abnormal head shape | 111 | 10−19 | Figure 7B | 0.42 |
| % abnormal tail bending | 111 | 10−19 | Figure 7C | 0.34 |
| % broken tails | 111 | 10−19 | Figure 7D | 0.07 |
| Sperm motility t = 10 min | ||||
| % motile | 116 | 10−18 | Figure 8A | 0.42 |
| VCL | 116 | 10−18 | Figure 8C | 0.68 |
| % vigorous | 116 | 10−18 | Figure 9 | 0.53 |
| % hyperactive | 116 | 11−18 | Figure 9 | 0.33 |
| Sperm motility t = 90 min | ||||
| % motile | 105 | 10−16 | Figure 8B | 0.60 |
| VCL | 105 | 10−16 | Figure 8D | 0.71 |
| % vigorous | 105 | 10−16 | Figure 9 | 0.73 |
| % hyperactive | 105 | 10−16 | Figure 9 | 0.40 |
| Sperm metabolism | ||||
| Lactate production | 61 | 4−11 | Figure 10 | 0.29 |
For each trait, the table lists the total number of mice sampled, the range of samples measured/founder strain, the figure reporting values for that trait and its narrow-sense heritability (h2) as defined in the Materials and Methods. na, not available; VCL, curvilinear velocity.