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. 2015 Oct 13;5(12):2671–2683. doi: 10.1534/g3.115.020172

Table 1. Phenotypes measured in the eight founder strains of the Collaborative Cross.

Trait No. Samples Range of Samples per Founder Figure h2
Age 248 na Figure S1 na
Weights
 Body 231 19−38 Figure 1A 0.84
 Mean testis 218 20−38 Figure 1B 0.71
 Mean epididymis + vas deferens 170 12−30 Figure 1C 0.70
 Seminal vesicles 217 20−38 Figure 1D 0.51
Histology
 Number of tubules 208 17−36 Figure 3A 0.50
 Mean tubule radius 208 17−36 Figure 3B 0.57
 Seminiferous epithelium length 208 17−36 Figure 3C 0.48
 # of tubules with vacuoles 207 16−36 Figure 4A 0.35
 # of tubules with many vacuoles 207 16−36 Figure 4B 0.39
 # of tubules with germ cell loss 141 12−26 Figure S4 0.15
 # of tubules with abnormal germ cells 207 16−36 Figure S4 0.12
 # of tubules with germ cell sloughing 207 16−36 na 0.11
Sperm count
 106/mouse 171 9−32 Figure 6A 0.38
 103/mg testis 159 9−30 Figure 6B 0.27
 103/seminiferous epithelium length 152 8−28 Figure 6C 0.22
Sperm morphology
 % normal 111 10−19 Figure 7A 0.47
 % abnormal head shape 111 10−19 Figure 7B 0.42
 % abnormal tail bending 111 10−19 Figure 7C 0.34
 % broken tails 111 10−19 Figure 7D 0.07
Sperm motility t = 10 min
 % motile 116 10−18 Figure 8A 0.42
 VCL 116 10−18 Figure 8C 0.68
 % vigorous 116 10−18 Figure 9 0.53
 % hyperactive 116 11−18 Figure 9 0.33
Sperm motility t = 90 min
 % motile 105 10−16 Figure 8B 0.60
 VCL 105 10−16 Figure 8D 0.71
 % vigorous 105 10−16 Figure 9 0.73
 % hyperactive 105 10−16 Figure 9 0.40
Sperm metabolism
 Lactate production 61 4−11 Figure 10 0.29

For each trait, the table lists the total number of mice sampled, the range of samples measured/founder strain, the figure reporting values for that trait and its narrow-sense heritability (h2) as defined in the Materials and Methods. na, not available; VCL, curvilinear velocity.