Table 1.
Variables | All patients (n = 77) | Propensity score matched patients (50 pairs) | ||||
---|---|---|---|---|---|---|
Normalized group | Non-normalized group | P | Normalized group | Non-normalized group | p | |
(n = 37) | (n = 40) | (n = 25) | (n = 25) | |||
No. of patients (%) | No. of patients (%) | No. of patients (%) | No. of patients (%) | |||
Age (years) | 0.279 | 0.929 | ||||
Median | 62 | 59 | 58 | 60 | ||
Range | 47–78 | 39–78 | 50–69 | 39–78 | ||
Gender | 0.550 | 0.747 | ||||
Male | 29 (78.4) | 29 (72.5) | 19 (76.0) | 18 (72.0) | ||
Female | 8 (21.6) | 11 (27.5) | 6 (24.0) | 7 (28.0) | ||
ECOG PS | 0.197 | 0.156 | ||||
0 | 23 (62.2) | 19 (47.5) | 16 (64.0) | 11 (44.0) | ||
1–2 | 14 (37.8) | 21 (52.5) | 9 (36.0) | 14 (56.0) | ||
Child-Pugh classification | 0.945 | 0.480 | ||||
A | 28 (75.7) | 30 (75.0) | 19 (76.0) | 21 (84.0) | ||
B | 9 (24.3) | 10 (25.0) | 6 (24.0) | 4 (16.0) | ||
Viral etiology | 0.402 | 1.000 | ||||
HBs-Ag (+) | 29 (78.4) | 28 (70.0) | 20 (80.0) | 20 (80.0) | ||
HBs-Ag (−) | 8 (21.6) | 12 (30.0) | 5 (20.0) | 5 (20.0) | ||
Tumor size (cm) | 0.488 | 0.344 | ||||
Median | 2.0 | 1.7 | 2.1 | 1.6 | ||
Range | 0.8–4.5 | 1.0–4.4 | 1.0–4.5 | 1.2–3.6 | ||
Initial AFP (ng/mL) | 0.187 | 0.655 | ||||
Median | 48.6 | 128.0 | 50.2 | 113.0 | ||
Range | 20.8–1870.0 | 20.3–3250.0 | 21.2–1870.0 | 20.3–2490.0 | ||
ALT | 0.093 | 0.981 | ||||
Median | 25 | 28.5 | 27 | 25 | ||
Range | 9–55 | 11–185 | 9–55 | 14–116 | ||
Albumin | 0.383 | 0.395 | ||||
Median | 3.6 | 3.4 | 3.4 | 3.6 | ||
Range | 2.4–4.5 | 2.4–4.7 | 2.4–4.5 | 2.9–4.7 | ||
Bilirubin | 0.841 | 0.804 | ||||
Median | 1.1 | 1.1 | 1.0 | 1.0 | ||
Range | 0.5–3.5 | 0.6–6.2 | 0.5–2.9 | 0.6–6.2 | ||
INR | 0.550 | 0.514 | ||||
Median | 1.1 | 1.1 | 1.2 | 1.1 | ||
Range | 0.9–1.5 | 0.9–1.7 | 0.9–1.5 | 0.9–1.7 | ||
Radiation dose | 0.909 | 0.743 | ||||
Median | 45 | 45 | 45 | 45 | ||
Range | 36–60 | 36–60 | 36–60 | 36–60 |
Abbreviations: ECOG PS Eastern Cooperative Oncology Group performance status, HBs-Ag hepatitis B surface-antigen, AFP alpha-fetoprotein, ALT alanine aminotransferase, INR international normalized ratio