Table 1.
Body and reproductive tissue weights of control and alcohol-induced male albino rats treated with the T. conophorum leaf extract
Parameters | Control | Alcohol group | 50 mg/kg extract | 500 mg/kg extract | 1000 mg/kg extract | 1.04 mg/kg drug |
---|---|---|---|---|---|---|
Initial body weight (g) | 348 ± 8.66 | 284 ± 13.11 | 292 ± 21.03 | 292 ± 22.23 | 294 ± 18.52 | 298 ± 16.52 |
Final body weight (g) | 368 ± 7.81 | 325 ± 9.07 | 297 ± 17.95 | 312 ± 16.52 | 295 ± 15.59 | 272 ± 18.94 |
Weight gain/loss (%) | 5.75 | 14.44* | 1.71* | 6.85* | 0.34* | −8.72* |
Right testis | ||||||
Absolute weight (g) | 2.03 ± 0.15 | 1.23 ± 0.03 | 1.73 ± 0.13 | 2.07 ± 0.12 | 2.08 ± 0.02 | 1.80 ± 0.13 |
Weight (g/ 100 g BW) | 0.74 ± 0.00 | 0.32 ± 0.05* | 0.49 ± 0.01* | 0.56 ± 0.08 | 0.70 ± 0.03 | 0.72 ± 0.09 |
Left testis | ||||||
Absolute weight (g) | 2.17 ± 0.45 | 0.99 ± 0.04* | 1.67 ± 0.06* | 2.14 ± 0.19 | 2.15 ± 0.08 | 2.07 ± 0.16 |
Weight (g/ 100 g BW) | 0.69 ± 0.02 | 0.22 ± 0.02* | 0.55 ± 0.06 | 0.57 ± 0.12 | 0.58 ± 0.02 | 0.51 ± 0.02 |
Epididymis | ||||||
Absolute weight (g) | 1.47 ± 0.41 | 0.61 ± 0.05* | 1.05 ± 0.16 | 1.40 ± 0.39 | 1.43 ± 0.08 | 1.42 ± 0.11 |
Weight (g/ 100 g BW) | 0.50 ± 0.03 | 0.18 ± 0.05* | 0.34 ± 0.02 | 0.37 ± 0.12 | 0.39 ± 0.05 | 0.31 ± 0.02 |
Seminal vesicle | ||||||
Absolute weight (g) | 1.09 ± 0.41 | 0.29 ± 0.05* | 0.40 ± 0.06* | 0.95 ± 0.11 | 0.96 ± 0.08 | 0.96 ± 0.07 |
Weight (g/ 100 g BW) | 0.46 ± 0.03 | 0.08 ± 0.01* | 0.14 ± 0.02* | 0.17 ± 0.03* | 0.35 ± 0.04 | 0.15 ± 0.02* |
Prostate gland | ||||||
Absolute weight (g) | 1.20 ± 0.22 | 0.40 ± 0.07* | 0.84 ± 0.18 | 1.16 ± 0.10 | 1.21 ± 0.18 | 1.17 ± 0.19 |
Weight (g/ 100 g BW) | 0.60 ± 0.00 | 0.12 ± 0.05* | 0.20 ± 0.03* | 0.29 ± 0.03* | 0.51 ± 0.06 | 0.26 ± 0.02* |
Data are expressed as mean ± SD, n = 5. *Significant (p < 0.0001) compared with the control group