Table 1.
Patient characteristics
| n (%) | Acute GI toxicity | P value | ||
|---|---|---|---|---|
| N = 63 | Grade < 2 | Grade ≥2 | ||
| N = 27 | N = 36 | |||
| Age (years) | ||||
| Median (range) | 55 (30–78) | 55 (30–78) | 57 (35–74) | |
| Mean (SD) | 56 (10) | 55 (11) | 57 (10) | 0.388a |
| Gender | ||||
| Male | 45 (71.4) | 16 | 29 | 0.092b |
| Female | 18 (28.6) | 11 | 7 | |
| T stage | ||||
| T1 | 0 | 0 | 0 | 0.759b |
| T2 | 3 (4.8) | 2 | 1 | |
| T3 | 33 (52.4) | 14 | 19 | |
| T4 | 27 (42.8) | 11 | 16 | |
| N stage | ||||
| Negative | 4 (6.3) | 2 | 2 | 1.000b |
| Positive | 59 (93.7) | 25 | 34 | |
| Tumor volume (cc) | ||||
| Median (range) | 92 (20–318) | 55 (20–135) | 83 (26–318) | |
| Mean (SD) | 91 (72) | 59 (25) | 116 (86) | 0.0004a |
| Tumor location (cm from the anal verge) | ||||
| Median (range) | 6 (2–12) | 5 (3–10) | 6(2–12) | |
| Mean (SD) | 6 (2) | 6 (2) | 6 (2) | 0.738a |
| Pre-existing number of daily bowel movements | ||||
| 1 | 6 (9.5) | 4 | 2 | 0.184b |
| 2–3 | 25 (39.7) | 13 | 12 | |
| 4–6 | 25 (39.7) | 9 | 16 | |
| ≥ 7 | 7 (11.1) | 1 | 6 | |
aIndependent T test; bExact test