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CoA administration allows normal development in P2-MO-injected embryos. Morphological comparison at 48 hpf of ST-MO- (A, B) and P2-MO-injected embryos (C, D) with P2-MO-injected embryos treated with 100 μM CoA (E, F). The magnification of heads (A–E) and tails (B–F) of representative embryos is shown. Addition of CoA to fish-water at blastula stage prevents all morphological alterations observed in embryos upon pank2 down-regulation.
