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pank2 knock-down affects trunk vessel integrity. WISH analysis of fli1a expression at 26 hpf in ST-MO- and P2-MO-injected embryos (A, A’, B, B’). We injected 1 pmol/embryo of ST-MO (C) and P2-MO (D) in Tg(gata1a:dsRed-fli1a:EGFP) embryos and analyzed the phenotype by confocal microscopy at 40 hpf. Abbreviations: DA, dorsal aorta; CV, caudal vein; ISVS, intersegmental vessels..
