Table 1.

Main morphological alterations observed in P2-MO-injected embryos.

Morphological defects	24 hpf	48 hpf
Altered brain morphology	+++	+++
Edema in hindbrain–midbrain ventricle (hydrocephalus)	+	+++
Edema in the caudal plexus	+	+++
Reduced heart beating rate	+	+++
Reduced blood circulation	+	++

+++ = strong alteration, ++ = moderate alteration, + = mild alteration.