. Author manuscript; available in PMC: 2016 Aug 1.

Published in final edited form as: Int J Radiat Oncol Biol Phys. 2015 May 1;92(5):1053–1059. doi: 10.1016/j.ijrobp.2015.04.039

Table 4. Summary of high-risk clinical target volume agreement statistics for RPS1 and RPS2.

Agreement parameter	RPS1	RPS2
Maximum volume (cc)	1333.6	974.6
Minimum volume (cc)	52.8	406.5
Mean volume (cc)	640.2	666.3
Standard deviation (SD)	316.3	216.0
SD as a % of mean volume	49.4	32.4
STAPLE 95 consensus volume (cc)	821.1	811.7
Intersection volume IV (cc)	0.0	63.7
IV as a % of mean volume	0	9.6
Union volume (cc)^*	1734.5	1499.2
Mean agreement sensitivity (±SD)	0.60 ± 0.22	0.68 ± 0.19
Mean agreement specificity (±SD)	0.98 ± 0.03	0.98 + 0.03
Overall kappa statistic (P value)	0.50 (<.0001)“Moderate”	0.57 (<.0001)“Moderate”

Abbreviation: STAPLE = simultaneous truth and performance level estimation. Other abbreviations as in Table 1.

Union volume is the largest volume assuming outermost contours.