Table 1. Number of deaths per group, biochemical serum and cell viability parameters in the six experimental groups.
| Parameters | Control (n = 9) | CIN (n = 9) | NAC (n = 6) | V10 (n = 9) | V100 (n = 9) | V300 (n = 7) | P |
|---|---|---|---|---|---|---|---|
| Body weight (g) | 37±2 | 40±1 | 38±1 | 37±1 | 38±1 | 40±2 | 0.65 |
| Number of deaths/group | 0% | 40%* | 25% | 44%* | 23% | 12% | 0.01 |
| Blood urea (mg/dL) | 66±2 | 259±31* | 250±50* | 244±33* | 209±34* | 136±22 # | <0.0001 |
| Serum creatinine (mg/dL) | 0.16±0.03 | 0.63±0.17* | 0.44±0.15 | 0.41±0.13 | 0.32±0.06 | 0.12±0.03 # | <0.005 |
| Viability of cortex renal cells (%) | 98.0±0.1 | 96.6±0.3* | 97.2±0.3 | 96.7±0.5 | 97.9±0.2 | 98.3±0.3 # | 0.0002 |
| Viability of medullary renal cells (%) | 98.5±0.2 | 96.2±0.3* | 96.9±0.4 | 95.3±0.6* | 97.6±0.3 | 98.5±0.3 # | <0.0001 |
The values are presented as the mean ± SEM for n = 6 to 9 animals per group.
* p < 0.05 vs. Control group.
# p < 0.05 vs. CIN group.