Fig 1. Heatmap showing temporal trends in expression among genes with pregnancy-associated expression, compared to pre-pregnancy levels in healthy women.

Log-transformed (log₂) values of the average fold change in expression compared to pre-pregnancy levels are plotted. Only genes that exhibited 2-fold or higher change in expression (compared to healthy pre-pregnancy baseline levels) in any trimester are shown. These patterns were similar in healthy women and in women with RA.