Table 3. KEGG pathway and Gene Ontology Biological process categories of the genes showing association with RA.

Pathway / biological process	Genes
mTOR signaling pathway	ULK1, AKT1
Toll-like receptor signaling pathway	IKBKG, AKT1, TOLLIP
Metabolic pathways	MAN2A2, GAA, GALC, CSGALNACT1, MAOA, NDUFV3, ABAT, LIPC, DBT, PISD
Fatty acid metabolic process	FADS1, FADS2, FADS3, ABAT, AKT1, LIPC, SCAP
Cellular polysaccharide metabolic process	GAA, AKT1, PYGM, CSGALNACT1
Intracellular transport of viral material	VPS37C, VPS37B
Neurotransmitter catabolic process	MAOA, ABAT
t-RNA binding	SLFN11, IGHMBP2
DNA helicase activity	IGHMBP2, HELB
Catalytic activity	GAA, TUBB2A, PYGM, SPTSSB, ACAP1, ULK1, ERCC4, RNF43, IGHMBP2, ABAT, GRK6, KIF21B, PISD, SPPL2A, FADS3, ECHDC3, TPST1, NDUFV3, DBT, UBE2M, CARS2, DCTN1, PLK3, FADS1, FADS2, AKT1, ADCK3, GALC, HELB, UFSP1, PPM1F, USP10, PGLYRP1, LIPC, ALK, MAN2A2, PRDX5, MAOA, CSGALNACT1, DTD1, TRIM36
GTPase activator activity	ARHGAP9, GMIP, ARHGAP27, ACAP1, RAP1GAP2

Up-regulated genes are shown in normal font and downregulated genes are in italics.