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. 2015 Dec 18;10(12):e0145251. doi: 10.1371/journal.pone.0145251

Table 3. Genes encoding Tricarboxicilic Acid Cycle enzymes in the B. pertussis Tohama I genome.

TCA cycle reaction Gene name Systematic name Encoded Protein
pyruvate → acetyl-CoA aceE BP0993 pyruvate dehydrogenase component E1
pyruvate → acetyl-CoA aceE BP1121
pyruvate → acetyl-CoA aceF BP0994 pyruvate dehydrogenase complex dihydrolipoamide-acetyltransferase
pyruvate → acetyl-CoA odhL BP1126 2-oxoglutarate dehydrogenase complex subunit dihydrolipoamide dehydrogenase
pyruvate → acetyl-CoA lpdA BP0995lpd dihydrolipoamide dehydrogenase
pyruvate → acetyl-CoA lpdA BP0618lpd
pyruvate → acetyl-CoA pdhA BP0629 pyruvate dehydrogenase component E1 subunitα
acetyl-CoA+ oxaloacetate→ citrate gltA BP2358 type II citrate synthase
citrate →isocitrate (intermediary: cis-aconitate) acnA BP2014 aconitate hydratase
citrate →isocitrate (intermediary: cis-aconitate) acnB BP2021 bifunctional aconitate hydratase 2
isocitrate→ α-ketoglutarate icd BP2488 isocitrate dehydrogenase
α-ketoglutarate→ succinyl-CoA odhB BP1125 dihydrolipoamide succinyltransferase
α-ketoglutarate→ succinyl-CoA sucA BP1124 2-oxoglutarate dehydrogenase
α-ketoglutarate→ succinyl-CoA odhL BP1126 2-oxoglutarate dehydrogenase complex subunit dihydrolipoamide dehydrogenase
α-ketoglutarate→ succinyl-CoA lpdA BP0995lpd dihydrolipoamide dehydrogenase
α-ketoglutarate→ succinyl-CoA lpdA BP0618lpd
succinyl-CoA→succinate sucD BP2540 succinyl-CoA synthase subunit α
succinyl-CoA→succinate sucC BP2541 succinyl-CoA synthase subunit β
succinate→ fumarate sdhA BP2361 succinate dehydrogenase flavoprotein (FAD) subunit
sdhB BP2360 succinate dehydrogenase iron-sulfur subunit
succinate→ fumarate sdhC BP2363 succinate dehydrogenase cytochrome B subunit
sdhD BP2362 succinate dehydrogenase hydrophobic membrane anchorprotein
fumarate →malate fumC BP0248 fumarate hydratase
malate→ oxaloacetate mdh BP2365 malate dehydrogenase
malate→ pyruvate maeB BP1120 NADP-dependent malic enzyme
malate→ pyruvate maeB BP3456
malate→ pyruvate maeB BP1064