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. 2015 Dec 18;10(12):e0145247. doi: 10.1371/journal.pone.0145247

Fig 1. Hyperthermia induces upregulation of neurofilament protein-expression.

Fig 1

(A) Neurofilament (NF) immunostaining in the hippocampus of a normothermic (NT) control animal, 14 days post-hyperthermia exposure. Square marks subfield enlargement; panel B. (B) Immunostaining for NF in the stratum lucidum of NT control animal (left panel) and in hyperthermia-exposed (HT) littermate (right panel). (C) Comparison of NF-based DAB staining in the stratum lucidum between NT and HT littermates. All HT (n = 10) animals showed increased DAB-staining in the stratum lucidum. Pair-wise comparison of DAB-staining intensities showed increased NF expression in HT animals compared to NT littermates (n = 10), Wilcoxon signed-rank test, * indicates a significance of P = 0.0049. Tukey-style box plots. Scalebars: 100 μm.