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. 2015 Dec 18;10(12):e0145247. doi: 10.1371/journal.pone.0145247

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© 2015 Jongbloets et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 6 — (A) Normal expression of CNP in the hippocampus of a normothermic (NT) control animal 14 days post-hyperthermia exposure. Square marks subfield enlargement, panel B and C. (B) Expression of CNP in the stratum lucidum of NT control animal (left panel) and hyperthermia-exposed (HT) littermate (right panel). Arrows indicates CNP-positive staining in the stratum lucidum. (C) Comparison of CNP-based DAB staining in the stratum lucidum between NT and HT littermates. All HT animals showed increased DAB-staining in the stratum lucidum. Increased expression of CNP were observed in HT animals compared to NT littermates, Wilcoxon signed-rank test, * indicates P = 0.0078. Tukey-style box plots. Scalebars: 100μm.