Table 1. Demonstration of feasibility of detecting asymptomatic infection among household members co-habitating with a prior symptomatic case using PCR-Southern blot of Leishmania kDNA (Phase1).
| At least one kDNA positive sample | |||
|---|---|---|---|
| Family/ household | Index Case Clinical history of leishmaniasis and LST(+) a (n/N) b | Asymptomatic infection, LST(+) (n/N) a | Healthy LST(-) co-habitant, (n/N) a |
| 1 | 0/1 | 0/4 | 0/0 |
| 2 | 1/1 | 2/2 | 0/2 |
| 3 | 1/1 | 3/4 | 0/0 |
| 4 | 1/1 | 1/2 | 0/2 |
| 5 | 1/1 | 0/3 | 0/1 |
| Total (%) | 4/5 (80%) | 6/15 (40%) | 0/5 (0%) |
aLST, Leishmanin skin test
b Number of participants with at least one kDNA positive sample (n)/ Total number of participants (N)