Table 2. Hemodynamic variables.

	baseline	drug perfusion	ischemia	reperfusion
			30	30	60
Heart Rate (bpm)
con	334 ± 37	316 ± 36		238 ± 43*	249 ± 41*
sil	295 ± 40	305 ± 43		226 ± 117	244 ± 39
kt+sil	313 ± 57	306 ± 54		198 ± 109*	252 ± 56
kt	317 ± 32	298 ± 36		287 ± 48	256 ± 34
RPP (mmHg * bpm)
con	38004 ± 6029	35803 ± 6717		6021 ± 3845*	7840 ± 3220*
sil	34296 ± 4887	35525 ± 4167		4036 ± 2255*	5964 ± 2297*
kt+sil	36083 ± 6829	32697 ± 4745		6403 ± 5231*	6076 ± 2809*
kt	37895 ± 6834	33894 ± 3521		6300 ± 4834*	6736 ± 3338*
LVEDP (mmHg)
con	4 ± 2	5 ± 4	32 ± 13*	72 ± 12*	66 ± 9*
sil	5 ± 2	7 ± 3	30 ± 6*	70 ± 9*	64 ± 8*
kt+sil	4 ± 2	6 ± 3	31 ± 8*	64 ± 12*	60 ± 9*
kt	4 ± 2	6 ± 3	31 ± 9*	77 ± 10*	70 ± 8*
Coronary flow (ml * min -1 /g dry heart weight)
con	101 ± 15	100 ± 14		59 ± 5*	56 ± 3*
sil	95 ± 22	100 ± 21		66 ± 15*	59 ± 13*
kt+sil	100 ± 21	100 ± 21		61 ± 11*	57 ± 14*
kt	92 ± 20	89 ± 23		62 ± 6*	59 ± 7*

Data are mean±SD. con = control; sil = sildenafil; kt = kt5823. RPP = rate pressure product; LVEDP = left ventricular end-diastolic pressure.

*P<0.05 versus baseline.