Table 1. Patient characteristics.
Number of patients (%) (N = 80) | |
---|---|
Age, median (range) | 58 (26–77) |
Sex | |
Male | 50 (62.5%) |
Female | 30 (37.5%) |
ECOG performance status | |
0 | 62 (77.5%) |
1 | 18 (22.5%) |
Primary site of disease | |
Proximal colon | 16 (20.0%) |
Distal colon | 33 (41.3%) |
Rectum | 31 (38.8%) |
Number of metastatic organs | |
1 | 17 (21.3%) |
2 | 28 (35.0%) |
≥ 3 | 35 (43.8%) |
Number of previous palliative chemotherapy regimens | |
≤ 2 | 33 (41.3%) |
3 | 32 (40.0%) |
≥ 4 | 15 (18.8%) |
Disease status | |
Initially metastatic | 45 (56.3%) |
Recurrent | 35 (43.8%) |
Time from metastasis to enroll | |
Median months (range) | 24 (6–106) |
Previous chemotherapy agents used | |
Fluoropyrimidine | 80 (100%) |
Oxaliplatin | 80 (100%) |
Irinotecan | 80 (100%) |
Bevacizumab | 9 (11.3%) |
Cetuximab (in 45 KRAS WT) | 6 (13.3%) |