Table 3. Unadjusted predictors of survival to hospital discharge after cardiac arrest.

Characteristic	Odds ratio (95% CI)	P value
Baseline clinical characteristic
Age	0.99 (0.97 – 1.02)	0.54
Male sex	0.72 (0.31 – 1.71)	0.46
Shockable rhythm	3.41 (1.40 – 8.31)	0.007
Out-of-hospital arrest	1.31 (0.53 – 3.30)	0.56
Pittsburgh Cardiac Arrest Category	0.30 (0.18 – 0.51)	<0.001
Baseline SOFA score	0.76 (0.62 – 0.93)	0.008
Therapeutic hypothermia	0.04 (0.01 – 0.34)	0.004
Acute kidney injury
Immediate post-arrest	1.21 (0.50 – 2.91)	0.67
Within 72 hours	0.51 (0.17– 1.49)	0.22
Within 5 days	0.58 (0.20 – 1.74)	0.34
Biomarkers at enrollment
NGAL, per 25,000 ng/mL	0.58 (0.42 – 0.79)	<0.001
ICAM-1, per 10 ng/mL	0.73 (0.52 – 1.02)	0.07
Leptin, per 100 pg/mL	1.10 (0.81 – 1.50)	0.53
HMGB, per 10 ng/mL	0.95 (0.77 – 1.17)	0.61
NSE, per 10 pg/mL	0.85 (0.67 – 1.07)	0.17
S100B, per 0.1 pg/mL	0.65 (0.45 – 0.92)	0.01

Abbreviations: NGAL - Neutrophil gelatinase-associated lipocalin; ICAM-1 – Intracellular cell adhesion molecule 1; HMGB – High-mobility group protein B1; NSE – Neuron specific enolase.