Table 1. Demographic, Transplant-Related and Psychiatric Characteristics of the Sample, n=155.
| Characteristic | % | (No.) |
|---|---|---|
| Demographic | ||
| Age, years, mean (SD) | 51.8 | (12.0) |
| Male | 49.0 | (76) |
| Caucasian | 94.8 | (147) |
| Less than high school education | 49.0 | (76) |
| Transplant-related | ||
| Years since transplant, median (IQR) | 12.1 | (10.8-13.2) |
| Indication for transplant | ||
| COPD/emphysema | 43.2 | (67) |
| Pulmonary fibrosis (including sarcoidosis and scleroderma) | 31.0 | (48) |
| Cystic fibrosis | 15.5 | (24) |
| Other | 10.3 | (16) |
| Bilateral lung transplanta | 45.2 | (70) |
| Total length of stay for transplant, days, median (IQR) | 21 | (12-35) |
| Ischemia time of donor graft, minutes, mean (SD) | 308.7 | (95.6) |
| Induction immunosuppression | ||
| Alemtuzumab | 30.3 | (47) |
| Daclizumab | 29.7 | (46) |
| Rabbit antithymocyte globulin | 18.7 | (29) |
| None | 21.3 | (33) |
| Maintenance immunosuppression | ||
| Tacrolimus | 87.1 | (135) |
| Cyclosporine | 12.9 | (50) |
| CMV mismatch (Recipient-/Donor+)b | 27.4 | (42) |
| Acute cellular rejection during first year post-transplant | 65.8 | (102) |
| Lymphocytic bronchiolitis during first year post-transplant | 25.8 | (40) |
| Medical comorbidities | ||
| Insulin-dependent Type 2 diabetes pre-transplant | 5.8 | (9) |
| Insulin-dependent Type 2 diabetes during first year post-transplant | 18.1 | (28) |
| Dialysis-dependent chronic kidney disease pre- or during the first year post-transplant | 0.0 | (0) |
| Congestive heart failure pre- or during the first year post-transplant | 0.0 | (0) |
| Psychiatric | ||
| Major depressive disorder | ||
| Pre-transplantc | 40.9 | (63) |
| Received pharmacologic treatment | 44.4 | (28) |
| During first year post-transplantd | 19.9 | (30) |
| Received pharmacologic treatment | 70.0 | (21) |
| Anxiety disordere | ||
| Pre-transplantc | 25.3 | (39) |
| Received pharmacologic treatment | 41.0 | (16) |
| During first year post-transplante | 26.5 | (40) |
| Received pharmacologic treatment | 57.6 | (23) |
a
Includes 4 heart-lung recipients
b
n=153 because there was missing information on 2 donors
c
n=154 because there was insufficient information to determine whether 1 recipient had pre-transplant disorders
d
n=151 because there was insufficient information to determine whether 3 recipients had post-transplant disorders
e
Pre-transplant, 6 recipients had panic disorder only, 9 had GAD only and 7 had both disorders. Post-transplant, 14 recipients had panic only, 1 had GAD only, 19 had PTSD-T only, 3 had panic and GAD, and 3 had panic and PTSD-T
Abbreviations: IQR, interquartile range; COPD, chronic obstructive pulmonary disease; A1AT, α-1-antitrypsin deficiency