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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Shock. 2016 Jan;45(1):88–97. doi: 10.1097/SHK.0000000000000478

Figure 7. Effect of AP39 on plasma IL-12 levels in a renal ischemia-reperfusion model in the rat.

Figure 7

Renal I/R significantly increased plasma IL-12 levels; this increase was concentration-dependently reduced by AP39; most pronouncedly at the 0.3 mg/kg dose of the H2S donor. Data are shown as mean ± SEM of 10 animals; *p<0.05 show significant increases in the vehicle-treated I/R group, compared to the sham control; # p<0.05 shows a significant protective effect of AP39 in I/R compared to the I/R group treated with AP39 vehicle. Data are shown as mean ± SEM of 10 animals.