Table 2.
The presence of ILI symptoms and duration of each symptom between influenza vaccinated and unvaccinated cases (all influenza cases)
| Presence of Symptoms | Median duration with Symptoms1 (IQR) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Bivariate analysis | Multivariate analysis | Bivariate analysis | ||||||||
| Symptom | Unvaccinated n=44 | Vaccinated n=111 | P-value | OR2 | 95% CI | Unvaccinated n=44 | Vaccinated n=111 | P-value3 | ||
| Chills | 34 (77.3) | 92 (82.9) | 0.419 | 3 | (2, 5) | 4 | (2.5, 5) | 0.550 | ||
| Cough | 44 (100) | 110 (99.1) | 1.0004 | 7 | (6, 7) | 7 | (6, 7) | 0.179 | ||
| Rhinorrhea | 35 (79.6) | 88 (79.3) | 0.971 | 5.5 | (4, 7) | 5 | (3, 7) | 0.451 | ||
| Earache | 23 (52.3) | 47 (42.3) | 0.263 | 2 | (0, 4) | 1 | (0, 4) | 0.281 | ||
| Sneezing | 25 (56.8) | 57 (51.4) | 0.539 | 3 | (2, 5) | 3 | (0, 5) | 0.842 | ||
| Sore throat | 31 (70.5) | 88 (79.3) | 0.241 | 4 | (2, 6) | 5 | (2, 6) | 0.862 | ||
| Eye issues | 19 (43.2) | 47 (42.3) | 0.924 | 1.5 | (0, 4) | 2 | (0, 4) | 0.760 | ||
| Nausea | 19 (43.2) | 40 (36.0) | 0.409 | 1 | (0, 3) | 1 | (0, 3) | 0.646 | ||
| Vomiting | 5 (11.4) | 17 (15.3) | 0.525 | 0 | (0, 0) | 0 | (0, 0) | 0.446 | ||
| Diarrhea | 2 (4.6) | 12 (10.8) | 0.3524 | 0 | (0, 1) | 0 | (0, 1) | 0.245 | ||
| Hoarseness | 30 (68.2) | 82 (73.9) | 0.475 | 5 | (2, 6) | 4 | (2, 6) | 0.875 | ||
| Joint pain | 28 (75.7) | 89 (80.9) | 0.494 | 4 | (2, 6) | 4 | (2, 6) | 0.706 | ||
| Dyspnea | 28 (63.6) | 56 (50.5) | 0.137 | 4 | (1, 6) | 2 | (0, 5) | 0.013** | ||
| Myalgia | 30 (68.2) | 93 (83.8) | 0.031** | 3.31** | (1.22, 8.97) | 4 | (2, 6) | 4 | (2, 6) | 0.650 |
| Headache | 37 (84.1) | 99 (89.2) | 0.383 | 4 | (3, 6) | 4 | (3, 5) | 0.371 | ||
| Fatigue | 44 (100) | 102 (91.9) | 0.0614 | N/A5 | 6.5 | (5, 7) | 5 | (4, 7) | 0.016** | |
| Dizziness | 22 (50.0) | 42 (37.8) | 0.166 | 2.5 | (0, 5) | 1 | (0, 4) | 0.037** | ||
| Appetite loss | 37 (84.1) | 91 (82.0) | 0.755 | 5 | (3, 7) | 5 | (3, 6.5) | 0.764 | ||
| Abdominal pain | 16 (36.4) | 36 (32.4) | 0.640 | 1 | (0, 4) | 0 | (0, 2) | 0.069 | ||
| Chest pain | 25 (56.8) | 51 (46.0) | 0.222 | 3.5 | (0, 5) | 1 | (0, 4) | 0.057 | ||
| Fever >101°F | 31 (70.5) | 52 (46.9) | 0.008** | 0.24** | (0.10, 0.62) | N/A | N/A | N/A | N/A | N/A |
1
Any severity.
2
Odds ratios from multivariate logistic regression, adjusting for sex, influenza season and use of antiviral drugs. MVA is only performed on symptoms with p-value <0.05 in bivariate analysis.
3
P-value of exact test
4
By Mann-Whitney U test; equal variances assumed.
IQR: interquartile range, N/A: Not Available, 95% CI: 95% confidence interval
**
p<0.05.