Table 1. Characteristics of Study Participants in the Training and Validation Datasets.
| Training(n = 353) | Validation(n = 181) | |||||
|---|---|---|---|---|---|---|
| Variable | No. | % | No. | % | P | |
| HCC Count | 121 | 61 | ||||
| Age (years) | 0.3676 | |||||
| ≤50 | 51 | 42.1 | 30 | 49.2 | ||
| > 50 | 70 | 57.9 | 31 | 50.8 | ||
| Sex | 0.7486 | |||||
| Male | 103 | 85.1 | 53 | 86.9 | ||
| Female | 18 | 14.9 | 8 | 13.1 | ||
| Total bilirubin (mmol/l) | 0.4458 | |||||
| ≤18.8 | 99 | 81.8 | 47 | 77.0 | ||
| > 18.8 | 22 | 18.2 | 14 | 23.0 | ||
| ALT (U/l) | 0.2534 | |||||
| ≤44 | 78 | 64.5 | 34 | 55.7 | ||
| > 44 | 43 | 35.5 | 27 | 44.3 | ||
| Tumor size (cm) | 0.7096 | |||||
| ≤5 | 67 | 55.4 | 32 | 52.5 | ||
| > 5 | 54 | 44.6 | 29 | 47.5 | ||
| Tumor number | 0.142 | |||||
| Single | 93 | 76.9 | 55 | 90.2 | ||
| Multiple | 28 | 23.1 | 9 | 9.8 | ||
| AFP(ng/ml) | 0.4018 | |||||
| ≤400 | 81 | 66.9 | 37 | |||
| > 400 | 40 | 33.1 | 24 | |||
| Macrovascular invasion | 0.3116 | |||||
| Yes | 49 | 40.5 | 20 | 32.8 | ||
| No | 72 | 59.5 | 41 | 67.2 | ||
| cirrhosis | 0.0213 | |||||
| Yes | 77 | 63.6 | 49 | 80.3 | ||
| No | 44 | 36.4 | 12 | 19.7 | ||
| BCLC | 0.7167 | |||||
| 0+A | 70 | 57.9 | 37 | 60.7 | ||
| B+C | 51 | 42.1 | 24 | 39.3 | ||
| HbsAg | NA | |||||
| Positive | 121 | 100.0 | 61 | 100.0 | ||
| HBV Count | 95 | 60 | ||||
| Age (years) | 0.5111 | |||||
| ≤50 | 77 | 81.1 | 46 | 76.7 | ||
| > 50 | 18 | 18.9 | 14 | 23.3 | ||
| Sex | 0.9321 | |||||
| Male | 50 | 52.6 | 32 | 53.3 | ||
| Female | 45 | 47.4 | 28 | 46.7 | ||
| Total bilirubin (mmol/l) | 0.7382 | |||||
| ≤18.8 | 75 | 78.9 | 46 | 76.7 | ||
| > 18.8 | 20 | 21.1 | 14 | 23.3 | ||
| ALT (U/l) | < 0.001 | |||||
| ≤44 | 83 | 87.4 | 22 | 36.7 | ||
| > 44 | 12 | 12.6 | 38 | 63.3 | ||
| AFP(ng/ml) | NA | |||||
| ≤400 | 95 | 100.0 | 60 | 100.0 | ||
| Healthy Count | 137 | 60 | ||||
| Age (years) | 0.5747 | |||||
| ≤50 | 63 | 45.7 | 24 | 40.0 | ||
| > 50 | 74 | 53.6 | 36 | 60.0 | ||
| Sex | 0.4726 | |||||
| Male | 112 | 81.8 | 55 | 90.2 | ||
| Female | 15 | 18.2 | 5 | 8.3 | ||
| Total bilirubin (mmol/l) | 0.4838 | |||||
| ≤18.8 | 121 | 88.3 | 55 | 91.7 | ||
| > 18.8 | 16 | 11.7 | 5 | 8.3 | ||
| ALT (U/l) | 0.5871 | |||||
| ≤44 | 135 | 98.5 | 58 | 96.7 | ||
| > 44 | 2 | 1.5 | 2 | 3.3 | ||
| AFP(ng/ml) | NA | |||||
| ≤400 | 137 | 100.0 | 60 | 100.0 | ||
Abbreviations: AFP, alpha fetoprotein; BCLC, Barcelona Clinic Liver Cancer; ALT, alanine aminotransferase; HCC, hepatocellular carcinoma; HBV, chronic hepatitis B; %, the percentage of the total.
NA, not application.