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. 2015 Sep 1;30(1):262–275. doi: 10.1096/fj.15-277749

Figure 2.

Figure 2.

MAPK/ERK signaling regulates Id1 expression. A) Western blot shows the expression level of Id1 and β-actin at the indicated time points after serum deprivation in HepG2 cells. B and C) Western blots show the expression levels of β-catenin, ERK1/2, pERK1/2, Id1, and β-actin in HepG2 (B) or Hepa1-6 (C) cells treated with MEK (U0126), VEGF (axitinib), and β-catenin (IWR-1-endo) inhibitors or DMSO for 24 h. D) Id1 mRNA transcript levels in HepG2 and Hepa1-6 cells after treatment with DMSO or U0126 for 24 h.