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Susceptibility of promastigotes of L. infantum to oxidative and nitrosative stress
| L. infantum strain | IC50 (μM) | ||
|---|---|---|---|
| H2O2 | Menadione | NONOate | |
| ITMAP-263 | 43 ± 11 | 2.6 ± 0.4 | >4000 |
| IMT-151 | 92 ± 15 | 3.9 ± 0.2 (*) | 2190 ± 360 (*) |
| IMT-202 | 71 ± 29 | 4.7 ± 0.2 (*) | 1560 ± 530 (*) |
(*) p < 0.05, versus ITMAP-263)
