Table 1.
Descriptive statistics and high-risk cutpoint for biomarkers used to compute total allostatic load
| Descriptive variables | N | M | SD | High-risk cutpoint (≥) |
|---|---|---|---|---|
| Cardiovascular | ||||
| Resting SBP (mmHg) | 985 | 130.98 | 17.69 | 143.00 |
| Resting DBP (mmHg) | 985 | 74.96 | 10.20 | 82.00 |
| Resting hear rate (bpm) | 984 | 70.57 | 11.07 | 77.00 |
| Metabolic - lipids | ||||
| BMI | 985 | 29.10 | 5.91 | 32.31 |
| WHR | 984 | 0.89 | 0.10 | 0.97 |
| Triglycerides (mg/dL) | 983 | 130.12 | 79.03 | 160.00 |
| HDL Cholesterol (mg/dL) | 983 | 54.68 | 17.45 | 41.37 |
| LDL Cholesterol (mg/mL) | 983 | 106.59 | 35.13 | 128.00 |
| Metabolic - glucose metabolism | ||||
| Glycosylated hemoglobin (HbA1c) | 981 | 5.98 | 0.89 | 6.10 |
| Fasting glucose (mg/dL) | 980 | 100.04 | 21.58 | 105.00 |
| Insulin Resistance (HOMA-IR) | 979 | 3.29 | 3.49 | 4.05 |
| Inflammation | ||||
| IL-6 (pg/ml) | 985 | 2.78 | 2.79 | 3.18 |
| CRP (mg/L) | 980 | 2.68 | 3.95 | 3.18 |
| Fibrinogen (mg/dL) | 981 | 341.45 | 84.42 | 390.00 |
| sE-Selectin (ng/Mi) | 985 | 41.50 | 20.69 | 50.58 |
| sICAM-1 (ng/MI) | 985 | 286.18 | 99.79 | 329.65 |
| Sympathesic Nervous System | ||||
| Urine Epinephrine (ug/g creatine) | 969 | 2.04 | 1.29 | 2.54 |
| Urine Norepinephrine (ug/g creatine) | 975 | 27.79 | 13.11 | 33.33 |
| Hypothalamic Pituitary Adrean Axis | ||||
| Urine Cortisol (ug/g creatine) | 983 | 16.52 | 16.46 | 21.00 |
| Blood DHEA-s (ug/dL) | 981 | 106.15 | 76.23 | 51.00 |
| Parasympathetic Nervous System | ||||
| SDRR (msec) | 908 | 34.97 | 16.87 | 23.54 |
| RMSSD | 908 | 21.04 | 14.53 | 11.83 |
| Low frequency spectral power | 908 | 421.66 | 628.24 | 113.96 |
| High frequency spectral power | 908 | 245.58 | 403.73 | 54.16 |
| Allostaic load | 985 | 1.72 | 1.02 | |