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Six weeks of GDNF overexpression from distally transplanted SCs leads to enhanced muscle mass recovery. Percent muscle mass recovery of the (A) gastrocnemius muscle and (B) tibialis anterior muscle compared to the unoperated control. Data are represented by the mean ± SEM (n ≥ 6 animals per group). * denotes statistical significance from isograft (p < 0.05), + denotes significance from GDNF-SCs DS Dox6 (p < 0.05), and # denotes significance from all groups except isograft (p < 0.05).
