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. Author manuscript; available in PMC: 2016 Dec 3.
Published in final edited form as: Cell. 2015 Dec 3;163(6):1539–1554. doi: 10.1016/j.cell.2015.11.008

Figure 5. Genetic variation in individuals from different strains of the turquoise killifish.

Figure 5

A) Resequencing of individuals from different turquoise killifish strains (GRZ, MZM-0703, MZM-0403) with different reported lifespans in specific laboratory environments. SNPs: Single Nucleotide Polymorphisms.

B) Circos plot of the 100 longest scaffolds showing SNP density in resequenced individuals from different turquoise killifish strains (GRZ, MZM-0703, MZM-0403) versus the reference GRZ assembly.

C) Unique and shared SNPs between resequenced individuals from reported shorter-lived (GRZ) or longer-lived strains (MZM-0703 and MZM-0403) versus the reference GRZ assembly. Values in the Venn diagram should be multiplied by 1000 and are rounded for concision.

D) Non-synonymous SNPs specific to individuals from the longer-lived strains (MZM-0403 and MZM-0703) in genes encompassing the hallmarks of aging. Aging-related genes were obtained from the GenAge database (human and mouse combined, Table S4A). All presented aging-related genes had at least one variant with predicted functional effect by both SIFT and PROVEAN (bolded genes) or by SIFT or PROVEAN (non bolded genes) (see also Table S5B).