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. 2015 Oct 9;7(10):2929–2940. doi: 10.1093/gbe/evv191

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© The Author(s) 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 3.— — The mRNA structural effect caused by exonic SNPs as a function of DAF. (A) Structural entropy caused by exonic SNPs as a function of DAF; (B) MFE gap between two alleles (|ΔΔG_MFE|) as a function of DAF; (C) Structural distance between two alleles as a function of DAF; (D) Comparison of the structural entropy between SNPs located in 5′- and 3′-UTR; (E) Comparison of the structural entropy between nonsynonymous and synonymous SNPs. Each point represents the mean of the corresponding category. Error bars indicate the standard error of the mean.