. Author manuscript; available in PMC: 2016 Nov 1.

Published in final edited form as: Int J Surg. 2015 Aug 22;23(0 0):223–228. doi: 10.1016/j.ijsu.2015.07.724

Table 1.

Amino acid diversity of endothelial cell proteins

Specific non-Gal antigens^*	Gene name	Amino acid identity (%)
NM_214006.1	CD9^*; tetraspanin	89.5
NM_213888.1	CD46^*; MCP	47.4
NM_214170.1	CD59^*; protectin	48.0
NM_001163406	PROCR^*; EC protein C receptor	71.2
NM_001005726	ANAX2^*	98.2
NM_001244330.1	B4GALNT2	75.8
Common endothelial cell proteins
NM_213816	CD54; ICAM-1	53.6
NM_213891	CD106; VCAM	54.9
NM_001001631	CD102; ICAM-2	56.1
NM_214268	CD62E; E-selectin	58.2
NM_214086	CD34	64.7
NM_213907	CD31; PECAM	71.5
NM_001001649	CDH5; VE-Cadherin	78.9
XM_003358192	SCARF1; acetylated-LDL receptor	79.3
XM_005667691	CD36	83.0
NM_001083932	CD51; ITGAV, Vitronectin receptor	95.0

The percent amino acid identity of the porcine protein compared to the human sequence was calculated using the European Molecular Biology Laboratory EMBOSS WATER pairwise protein sequence alignment algorithm. On average these porcine genes show only 71% amino acid identity to the human homolog.

An induced antibody response has been reported to these endothelial cell membrane products after pig-to-baboon heterotopic cardiac xenotransplantation (33).