Table 3.

SAR Studies of the Entry Inhibitors MLS00876570 and MLS000877128

Sample ID	Structure	EC50 (μM)	Max Resp	Sample ID	Structure	EC50 (μM)	Max Resp
MLS000876570-01*		4.4668	−76.038	MLS000877128-01†		1.2589	−73.014
MLS000948303-01		7.0795	−55.607	MLS000913279-01		1.4125	−80.801
MLS000086763-01		10	−72.669	MLS000095189-01		2.8184	−67.008
MLS000519917-01		3.9811	−67.83	MLS000095186-01		5.0119	−42.656
MLS000086784-01		6.3096	−83.27	MLS000095191-01		6.3096	−73.5
MLS000519916-01		8.9125	−74.83	MLS000117605-01		11.2202	−64.827
MLS000948325-01		22.3872	−67.553	MLS000095192-01		14.1254	−75.426
MLS000730063-01		31.6228	−69.852	MLS000878431-01		22.3872	−38.647
MLS000519908-01		> 100	12.531	MLS000095190-01		> 100	−23.229
MLS000948314-01		> 100	−1.231	MLS000913230-01		> 100	−27.788

^*Lead compound chemotype 1;

^†lead compound chemotype 2.