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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Free Radic Biol Med. 2015 Oct 8;89:473–485. doi: 10.1016/j.freeradbiomed.2015.09.005

Figure 2.

Figure 2

APN attenuated TNF-α induced nitrotyrosine formation (A) and ICAM-1 expression (B) in control cells cultured with normal glucose/normal lipid (Control). After 72 hours of HUVEC exposure to HG/HL, APN failed to reduce TNF-α mediated nitrotyrosine production (A) and ICAM-1 expression (B). No significant alteration was observed in expression levels of AdipoR1, AdipoR2 and APPL1 (C). N=6–8 dishes/group from at least 4 different cell batches.**P<0.01 vs. TNFα+Vehicle.