Table 1.
Antimicrobial | MIC (µg/ml) | ||
---|---|---|---|
BPU-1 | Control1 | Fold change | |
Ampicillin | 1,024 | 2 | 512 |
Ampicillin-Clavulanic acid2 | 32 | 2 | 323 |
Ampicillin-Sulbactam2 | 1,024 | 2 | 03 |
Ampicillin-Tazobactam2 | 1,024 | 2 | 03 |
Piperacillin | 256 | 2 | 128 |
Ticarcillin | 8,192 | 4 | 2048 |
Carbenicillin | 8,192 | 4 | 2048 |
Oxacillin | 8,192 | 256 | 32 |
Cephalothin | 8 | 4 | 2 |
Cephalexin | 8 | 4 | 2 |
Cefotaxime | 0.125 | 0.031 | 4 |
Ceftriaxone | 0.125 | 0.031 | 4 |
Ceftazidime | 32 | 0.25 | 128 |
Cefoxitin | 8 | 4 | 2 |
Cefepime | 4 | 0.03 | 128 |
Aztreonam | 8 | 0.06 | 128 |
Imipenem | 0.25 | 0.125 | 2 |
Meropenem | 0.030 | 0.015 | 2 |
Doripenem | 0.045 | 0.030 | 1.5 |
Control strain E. coli JM83 with the pHF016 vector.
Clavulanic acid, sulbactam and tazobactam were used at a constant concentration of 4 µg/mL.
Fold change in comparison to the MIC value for ampicillin.