Table.
Distribution of baseline characteristics among entire eligible baseline sample and the subset with both baseline and follow-up data, overall and for knee symptoms and four OA outcomes*,†
| Overall | Outcome subpopulation |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Symptoms | Radiographic | Symptomatic | Severe radiographic | Severe symptomatic‡ | ||||||||
| Baseline Only (n=1,400) |
Analytic (n=1,518) |
Baseline Only (n =765) |
Analytic (n = 887) |
Baseline Only (n = 974) |
Analytic (n = 1,246) |
Baseline Only (n = 1,190) |
Analytic (n = 1,342) |
Baseline Only (n = 1,306) |
Analytic (n = 1,419) |
Baseline Only (n = 1,374) |
Analytic (n = 1,473) |
|
| % | % | % | % | % | % | % | % | % | % | % | % | |
|
Socio-demographic
characteristics |
||||||||||||
| Age (years) | ||||||||||||
| 45–54 | 31 | 37 | 36 | 41 | 37 | 41 | 35 | 40 | 32 | 39 | 31 | 37 |
| 55–64 | 23 | 31 | 22 | 32 | 25 | 31 | 23 | 31 | 24 | 30 | 23 | 31 |
| 65–74 | 28 | 25 | 28 | 21 | 25 | 23 | 28 | 23 | 28 | 24 | 29 | 24 |
| ≥75 | 17 | 8 | 14 | 7 | 13 | 5 | 15 | 6 | 16 | 7 | 17 | 8 |
| Sex | ||||||||||||
| Men | 47 | 41 | 51 | 44 | 49 | 42 | 48 | 42 | 47 | 41 | 47 | 41 |
| Women | 53 | 49 | 49 | 56 | 51 | 58 | 52 | 58 | 53 | 59 | 53 | 59 |
| Race | ||||||||||||
| Black | 22 | 14 | 23 | 12 | 21 | 13 | 22 | 14 | 21 | 14 | 22 | 14 |
| White | 78 | 86 | 77 | 88 | 79 | 87 | 78 | 86 | 79 | 86 | 78 | 86 |
| Marital status | ||||||||||||
| Never married | 3 | 3 | 3 | 3 | 4 | 3 | 4 | 3 | 4 | 3 | 4 | 3 |
| Married | 62 | 70 | 69 | 73 | 65 | 72 | 64 | 72 | 63 | 71 | 62 | 71 |
| Separated/Divorced | 12 | 8 | 10 | 7 | 12 | 9 | 12 | 8 | 12 | 8 | 12 | 8 |
| Widowed | 23 | 18 | 19 | 16 | 19 | 16 | 20 | 17 | 21 | 18 | 22 | 18 |
| Annual household income | ||||||||||||
| $0 – <$15,000 | 42 | 27 | 33 | 22 | 38 | 24 | 39 | 25 | 40 | 27 | 41 | 27 |
| 15,000 – <$35,000 | 24 | 30 | 26 | 31 | 25 | 31 | 25 | 31 | 25 | 31 | 24 | 30 |
| $35,000+ | 13 | 22 | 19 | 27 | 15 | 24 | 14 | 23 | 13 | 23 | 13 | 23 |
| Don't know | 9 | 8 | 9 | 7 | 9 | 8 | 9 | 8 | 10 | 8 | 9 | 8 |
| Refused | 12 | 12 | 13 | 13 | 14 | 13 | 13 | 13 | 12 | 12 | 12 | 12 |
| Highest education | ||||||||||||
| Less than high school | 27 | 14 | 22 | 9 | 24 | 13 | 25 | 13 | 26 | 14 | 27 | 14 |
| Some/completed high school | 48 | 54 | 47 | 53 | 49 | 54 | 49 | 54 | 50 | 54 | 48 | 54 |
| Greater than high school | 24 | 32 | 31 | 38 | 26 | 34 | 26 | 33 | 24 | 32 | 25 | 32 |
| Knee OA risk factors | ||||||||||||
| Self-reported BMI (kg/m2) at age 18 |
||||||||||||
| Underweight/Normal(<25) | 88 | 91 | 88 | 93 | 88 | 92 | 88 | 92 | 89 | 91 | 88 | 92 |
| Overweight/Obese (≥25) | 12 | 9 | 12 | 7 | 12 | 8 | 12 | 8 | 11 | 9 | 12 | 8 |
| Clinically measured baseline BMI (kg/m2) |
||||||||||||
| Underweight/Normal(<25) | 37 | 33 | 41 | 39 | 40 | 35 | 39 | 35 | 38 | 33 | 37 | 33 |
| Overweight (25-<30) | 39 | 43 | 39 | 43 | 40 | 43 | 39 | 43 | 40 | 43 | 39 | 44 |
| Obese (≥ 30) | 24 | 24 | 20 | 18 | 20 | 22 | 22 | 22 | 22 | 23 | 24 | 23 |
| Obese Class I (30-<35) | 17 | 18 | 16 | 14 | 15 | 17 | 16 | 17 | 16 | 17 | 16 | 17 |
| Obese Class ≥ II (≥35) | 7 | 7 | 4 | 4 | 6 | 5 | 6 | 5 | 6 | 6 | 7 | 6 |
| History of knee injury | ||||||||||||
| No | 84 | 84 | 93 | 92 | 86 | 87 | 86 | 87 | 85 | 85 | 85 | 85 |
| Yes | 16 | 16 | 7 | 8 | 14 | 13 | 14 | 13 | 15 | 15 | 15 | 15 |
|
Knee symptoms (pain, aching and/or stiffness) |
||||||||||||
| None | 56 | 60 | 10 | 10 | 62 | 66 | 66 | 68 | 58 | 63 | 58 | 61 |
| Yes | 44 | 40 | 0 | 0 | 38 | 34 | 34 | 32 | 42 | 37 | 42 | 39 |
| Severity of pain | ||||||||||||
| None | 57 | 61 | 10 | 10 | 62 | 66 | 67 | 68 | 59 | 63 | 58 | 61 |
| Mild | 11 | 16 | 0 | 0 | 9 | 15 | 8 | 14 | 11 | 15 | 12 | 16 |
| Moderate | 21 | 19 | 0 | 0 | 18 | 14 | 16 | 14 | 19 | 17 | 22 | 19 |
| Severe | 11 | 5 | 0 | 0 | 11 | 4 | 9 | 4 | 12 | 5 | 8 | 4 |
| KL grade | ||||||||||||
| 0 | 46 | 51 | 52 | 59 | 64 | 61 | 54 | 57 | 49 | 54 | 47 | 53 |
| 1 | 26 | 32 | 26 | 32 | 36 | 39 | 30 | 37 | 27 | 34 | 27 | 33 |
| 2 | 22 | 12 | 18 | 7 | 13 | 5 | 24 | 12 | 20 | 10 | ||
| 3 | 4 | 3 | 3 | 1 | 2 | 1 | 5 | 3 | ||||
| 4 | 2 | 1 | 1 | 0 | 0 | 0 | 2 | 1 | ||||
Distributions (percentages) differ from those presented in Table 2 because they were derived using baseline sampling weights which were based on 1990 Population in six townships in Johnston County. First follow-up weights (based on 2000 Population in six townships in Johnston County) were applied when estimating distributions and IRs for the analytic sample (i.e., those with both baseline and first follow-up data) to make estimates representative of the population in six townships in Johnston County.
Eligible respondents in overall population are those who did not have pre-existing knee symptoms and KL grade ≥ 2 at baseline; eligible respondents in each subpopulation are those who did not have the pre-existing outcome at interest at baseline. Baseline only are those respondents who were eligible at baseline but did not have follow-up data; analytic population are those with both baseline and first follow-up data.
Presence of symptoms (pain, aching, or stiffness) and severe pain
BMI, body mass index; K-L, Kellgren-Lawrence; OA, osteoarthritis