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Low-dose AB rescues neurons from PQ-mediated increases in oxidized glutathione (GSSG). NG108-15 cells were treated with 50 μM PQ with various doses of AB. AB was added 24 hours prior to PQ; cells were analyzed 48 hours after PQ administration. (a) Relative levels of reduced glutathione (GSH). N = 3. (b) Relative levels of oxidized glutathione (GSSG). N = 3. ∗ p < 0.05 versus No AB; Ψ p < 0.05 versus PQ-No AB.
