Table 4.

Multivariate association in osteogenic differentiation (*p < 0.05)

	ALP activity			Osteocalcin mRNA			ALP mRNA			Runx2 mRNA
	p	OR	95 % CI	p	OR	95 % CI	p	OR	95 % CI	p	OR	95 % CI
Interval from injury to surgeryb, < 90 days	0.263	2.416	0.515–11.337	0.009*	20.579	2.119–199.882	0.022*	6.527	1.308–32.557	0.047*	5.247	1.023–26.922
10 ≤ age <20 year-oldc	0.895	0.884	0.142–5.491	0.384	2.683	0.290–24.782	0.962	0.954	0.141–6.481	0.592	0.600	0.092–3.895
20 ≤ age <30 year-oldc	0.240	0.277	0.033–2.356	0.909	1.155	0.097–13.787	0.742	1.420	0.176–11.451	0.480	0.463	0.055–3.924
Sexa Female	0.030*	12.831	1.279–128.746	0.850	0.831	0.123–5.606	0.885	1.131	0.212–6.041	0.550	0.601	0.113–3.191
Meniscal injuryd	0.218	2.400	0.596–9.670	0.198	2.600	0.606–11.152	0.360	1.920	0.475–7.766	0.803	1.200	0.287–5.021
Chondral injuryd	0.000	0.000	0.000–0.000	1.000	1.000	0.081–12.270	0.000	0.000	0.000–0.000	0.913	1.150	0.093–14.188
Combined meniscal or chondral injuriesd	0.402	1.800	0.455–7.127	0.346	2.000	0.473–8.462	0.588	1.467	0.367–5.858	0.519	1.615	0.376–6.940

^aUse “male” category as reference

^bUse “interval more than 90 days” category as reference

^cUse “age more than 30-year old” category as reference

^dUse “no meniscal or chondral injuries” category as reference