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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Mol Cancer Res. 2015 Sep 9;13(12):1533–1543. doi: 10.1158/1541-7786.MCR-15-0237

Table 1.

Combination Index (CI) for the combination of mitomycin C and bortezomib under hypoxia (1% O2) was calculated using the CompuSyn software for LS174T and LS180 cancer cells.

Combination therapy Combination index
Mitomycin C (μg/ml) Bortezomib (nM) LS174T LS180
2 10 0.24 *** 0.25***
4 20 0.41** 0.33**
10 30 0.47** 0.41**
*

slight synergy;

**

moderate synergy;

***

strong synergy.