Figure 1.
Gene expression of leptin and leptin receptor in THP-1 macrophages exposed to adalimumab and ustekinumab: THP-1 macrophages were incubated for 18 h under the following conditions: (a) untreated control, (b) adalimumab 5 μg/mL, (c) ustekinumab 1 μg/mL, (d) ustekinumab 5 μg/mLL. Quantitative analysis for changes in leptin and leptin receptor mRNA level was performed using RT-PCR with GAPDH message as an internal standard. All results are presented as means ± SEM of three independent experiments. **P < 0.01 vs. control.