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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: J Immunol. 2015 Nov 20;196(1):310–316. doi: 10.4049/jimmunol.1501836

FIGURE 7. Irf7 is required for immune cytokine production.

FIGURE 7

WT, Irf3−/−, Irf7−/−, and DKO sera were collected pre-vaccination and 6 hours post DNA vaccination. Serum cytokines were quantified from individual mice at a 1:2 dilution using a BD Th1/Th2/Th17 cytokine kit. Shown are significant decreases in cytokines after vaccination with pH1HA encoding DNA vaccine: (A) TNF-α and (B) IL-6. Data are the averages ± SEM of 2 independent studies of 5 mice per group (Total N=10 per phenotype). *p<0.05, **p<0.01 versus control group.