Table 2.
Treatment groups | Respiration (breaths/min) | Blood Pressure (mmHg) | Heart Rate (bpm) | |||
---|---|---|---|---|---|---|
Emax (Mean ± SEM) | p-value | Emax (Mean ± SEM) | p-value | Emax (Mean ± SEM) | p-value | |
nTS before vehicle/after vehicle (n = 3) | 4.0 ± 2.0/2.0 ± 2.0 | 0.667 | 43.5 ± 1.57/49.8 ± 3.47 | 0.324 | 281.7 ± 6.00/282.3 ± 8.69 | 0.843 |
Pa5 before vehicle/after vehicle (n = 4) | 9.0 ± 3.87/6.0 ± 3.46 | 0.181 | 48.3 ± 7.11/48.6 ± 5.61 | 0.884 | 286.5 ± 26.18/302.7 ± 18.10 | 0.216 |
nTS before muscimol/after muscimol (n = 4) | 10.5 ± 2.87/9.0 ± 1.73 | 0.391 | 51.5 ± 4.64/38.3 ± 5.15 | 0.052 | 286.7 ± 15.60/277.7 ± 4 0.27 | 0.751 |
Pa5 before muscimol/after muscimol (n = 4) | 6.0 ± 3.46/25.5 ± 2.87 | 0.001* | 53.5 ± 4.79/50.5 ± 1.93 | 0.577 | 316.3 ± 10.65/309.5 ± 8.13 | 0.111 |
Baseline (prior to any treatments or stimulation) respiratory rate (breaths/min) = 46.93 ± 1.69; blood pressure (mmHg) = 60.34 ± 2.19; heart rate (bpm) = 301.93 ± 8.06.
Significantly different compared to before treatment.